image de fond demi-cercle noir

We are dedicated to provide high clinical benefits and financial returns, building innovative companies from the best research teams worldwide.

We gather execution-focused teams to deliver meaningful results.

Opportunity in rare disease is real and strong

VALUE over volume

High pricing per patient

Average annual price per patient with rare diseases 218k€ vs 13k€ for common diseases

high success rate

2X likelihood of success

Likelihood of success from Phase 1 to marketing authorization: 17% for orphan drugs vs 8% in general

high ROI

7.2X investment multiple

7.2x average investment multiple from Phase 1 to approval in orphan drugs vs. 2.1x for non-orphan

our investment thesis

OUR LEGACY

logo afm telethon

A relentless partner to address rare diseases

Fighting
rare diseases

since 1958

550+ FTEs and 215k+ volunteers

€1.7b invested in R&D for rare diseases

Renown expertise

to develop programs
for rare diseases

Network of 6,000+ medical and scientific experts in rare diseases and across all technology modalities

38 clinical trials on-going or under preparation on 28 different indications

Up to 200 new research projects funded every year

An association with a proven track-record

as venture-builder

Creation of Genosafe in 2003 – CRO for gene and cell therapy

Creation of BIMR in 2013 with BPIfrance Investment fund for rare diseases and innovative therapies – 7 companies supported

Creation of Yposkesi in 2016 – CDMO for gene and cell therapy

Creation of Atamyo in 2020 – Gene therapy biotech for muscular dystrophies

Contributed to the creation of 600+ direct jobs